Ingesting cocaine will create serious long term effects, both on the brain and on the body. Whether it is snorted, injected, or smoked, it has harmful, lasting effects that far out-weigh the short-term gains.
Effects To The Brain
Cocaine, in all its forms, is highly addictive. The first use creates the highest high, meaning that a user will never be able to achieve that same high again, no matter how many times they try. In fact, the brain adapts to cocaine and builds a tolerance, which means that each high is less effective than the previous. Drug users insatiably search for that first high, ingesting higher quantities more frequently in the process. Some of the long term issues include:
inability to enjoy natural highs of life
loss of interest in normal life activities
desperation for the next high
tolerance to lower quantities of substances
memories of the first high, causing cravings
high relapse risk
binging
anxiety, irritability, paranoia and panic
disorientation, confusion
discomfort, including aches, chills and itchiness
mood swings
restlessness
losing touch with reality due to psychosis
Because of the way cocaine enters the bloodstream and targets the brain, blocking the natural chemicals that create feelings of highs and lows, when a person is high on cocaine, they are enjoying the build-up of the blocked neurotransmitters, such as norepinephrine and dopamine, which are not being absorbed, therefore creating the high.
Effects To The Body
There are some long term effects that are inevitable no matter how the potent drug is ingested, and some that are specific to how it is ingested. Some of the general lasting effects of cocaine are:
intestinal issues: constricted blood vessels to the digestion system cuts off oxygen circulation, which can result in ulcers, gangrenous bowels, and even perforations in the intestines or stomach
high blood pressure: increased heart rates can put pressure on veins, which can cause heart disease, heart attacks, and arrhythmia
kidney failure: high blood pressure can lead to kidney failure
respiratory issues: blood pressure can contribute to lung and breathing problems, as can both snorting and smoking
strokes and seizures: constricted blood vessels in the brain can lead to seizures and violent behaviour, and strokes, even in younger people who aren’t usually at risk
malnourishment: cocaine users often experience a loss of appetite, since they crave the drug more than food. This leads to extreme weight loss and malnourishment in many users
sleep deprivation: many addicts experience loss of sleep because of highs and lows, and even experience hallucinations
sexual dysfunction: cocaine can cause sexual and reproductive issues in both male and female users, despite initial symptoms of heightened sexual arousal
depressing comedowns: when coming down from a high, addicts experience extreme lows that lead to depression and harmful behaviour